Neonatal serum bilirubin estimation.

Estimation of bilirubin binding capacity of neonatal serum.

One aim of laboratory investigation in neonatal jaundice is to prevent kernicterus from occurring. Estimation of the bilirubin-binding capacity of serum is an important measurement along with total bilirubin determination. With a convenient Sephadex competitive binding procedure, KERNLUTE provides information on whether or not the neonate's bilirubin-binding capacity has been exceeded. Further ...

Noninvasive estimation of serum bilirubin.

OBJECTIVE The aim of this study was to evaluate the accuracy and clinical usefulness of a new computer-driven, hand-held device (Chromatics Colormate III) to estimate serum bilirubin from skin-reflectance (skin color) of neonates. STUDY DESIGN A total of 2441 infants (both term and premature) at two hospitals had repeated measurements of transcutaneous bilirubin. Of these infants, 900 had one...

The estimation of serum bilirubin.

Estimation of bilirubin in serum.

Most methods of estimating the concentration of bilirubin in serum are based on the van den Bergh reaction in which bilirubin couples with diazotized sulphanilic acid to give red " azobilirubin," the reaction being facilitated by the addition of an activator or catalyst such as ethanol. The many modifications of this reaction can be classified into two groups: (a) those in which ethanol is used...

Reflections on the standardization of total bilirubin in neonatal serum.

A study is described on the standardization of the determination of neonatal total bilirubin. A wide variation in results was shown in surveys held in The Netherlands and Germany and the reasons for this variation were sought. The suitability of commercial bilirubin standards and direct reading instruments, widely used in the neonatal field, was tested by comparing all measurements with those o...